If you are not familiar with the term it might be easy to pronounce the name as “g-nome” or “ger-nome” but the “g” is silent so what’s you actually say is “nome”.
The Computer Software Which is also Called Gnome
However, just to add to the confusion, if you are talking about the computer software which has the same name as our small friends that we place in our homes, yards and gardens, then you will need to pronounce this as “G-nome”. Here is the official explanation of this.
